ورود
مقالات فارسیISIکنفرانسهاژورنالها

An Investigation of the Relationship Between HLA-CW۰۶ and Psoriasis in Iranian Patients Using Sequence-specific Primers

محل انتشار: مجله بین المللی آزمایشگاه پزشکی، دوره: 9، شماره: 2
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 125

فایل این مقاله در 6 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1607534

شناسه ملی سند علمی:

JR_JIML-9-2_008

تاریخ نمایه سازی: 2 اسفند 1401

چکیده مقاله:

Background and Aims: Psoriasis is a chronic inflammation of the skin caused by the proliferation of inappropriately differentiated horn cells, resulting in plaque psoriasis formation. It is not often fatal, and it may lead to physical disabilities and severe mental stress in which professional and social activities could be highly affected. It is generally accepted that the human leukocyte antigen (HLA)-CW۰۶ allele has a significant role in the onset of this disease. Materials and Methods: This study determines the association between the HLA-CW۰۶ allele and psoriasis. The present case-control study was conducted to evaluate the relation between HLA-CW۰۶ and psoriasis in a population in Iran. This study was performed on ۳۰ samples of patients with psoriasis. Results: The results of polymerase chain reaction- sequence-specific primers for the detection of HLA-CW۰۶ showed positive amplification in ۷ out of ۳۰ psoriasis patients as compared to ۴ among ۳۰ controls. Conclusion: This study showed that due to different allele frequencies associated with psoriasis in different parts of the world, it seems that other genetic and epigenetic factors may be involved in this disease.

کلیدواژه ها:

HLA-CW۰۶ ، Inflammatory disease ، MHC ، PCR-SSP ، Psoriasis

نویسندگان

زهرا شاکری فینی

Department of Microbiology, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran

پیام خیرمند پاریزی

Cellular, Molecular, and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran ۳ Genome Medical Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

سید علیرضا اسماعیلی

Immunology Research Center, Bu‐Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran ۵ Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

عباس صمدی خوزانی

Department of Biology, Faculty of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran

سارا حسینی

Immunology Research Center, Bu‐Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran ۵ Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

مصطفی جعفرپور

Department of Microbiology, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • . Mehrmal S, Uppal P, Nedley N, Giesey RL, Delost ...
  • . Bhende S, Parwe S. Role of Nitya Virechana and ...
  • . Takahashi H, Nakamura K, Kaneko F, Nakagawa H, Iizuka ...
  • . Atabati H, Esmaeili SA, Saburi E, Akhlaghi M, Raoofi ...
  • . Eppinga H, Poortinga S, Thio HB, Nijsten TE, Nuij ...
  • . Merola JF, Li T, Li WQ, Cho E, Qureshi ...
  • . Guinot C, Latreille J, Perrussel M, Doss N, Dubertret ...
  • . Schön MP. Animal models of psoriasis: a critical appraisal. ...
  • . Cai Y, Fleming C, Yan J. New insights of ...
  • . Martins AM, Ascenso A, Ribeiro HM, Marto J. The ...
  • . Dand N, Satveer K, Francesca C, Catherine H. S, ...
  • . Hugh JM, Weinberg JM. Pathophysiology of psoriasis/novel pathways, in ...
  • . Nedoszytko B, Szczerkowska-Dobosz A, Stawczyk-Macieja M, Owczarczyk-Saczonek A, Reich ...
  • . Esmaeili A, Zamani Taghizadeh Rabe S, Mahmoudi M, Rastin ...
  • . Ghodke Y, Joshi K, Chopra A, Patwardhan B. HLA ...
  • . Sharifi A, Ghadiri A, Salimi A, Ghandil P, Esmaeili ...
  • . Chen L, Tsai TF. HLA‐Cw۶ and psoriasis. Br J ...
  • . Raychaudhuri SK, Maverakis E, Raychaudhuri SP. Diagnosis and classification ...
  • . Dogra S, Bishnoi A. Childhood psoriasis: What is new ...
  • . Fry L, Baker BS, Powles AV. Psoriasis- A possible ...
  • . Sladek R, Rocheleau G, Rung J, Dina C, Shen ...
  • . Samadi-Khouzani A, Parizi PK, Ghafari F, Esmaeili SA, Peymani ...
  • . Zeng J, Luo S, Huang Y, Lu Q. Critical ...
  • . Peralta C, Hamid P, Batool H, Al Achkar Z, ...
  • . Unissa R, Kumar PM, Pasha M, Begum S, Maheswari ...
  • . Enamandram M, Kimball AB. Psoriasis epidemiology: the interplay of ...
  • . Knight J, Spain SL, Capon F, Hayday A, Nestle ...
  • . Sabat R, Philipp S, Höflich C, Kreutzer S, Wallace ...
  • . Chandra A, Lahiri A, Senapati S, Basu B, Ghosh ...
  • . Diani M, Altomare G, Reali E. T cell responses ...
  • . Pasch MC. Nail psoriasis: a review of treatment options. ...
  • . Albanesi C. Immunology of psoriasis. Clinic Immunol. Elsevier; ۲۰۱۹: ...
  • . Dadwal A, Mishra N, Narang RK. Novel topical nanocarriers ...
  • . Mallon E, Newson R, Bunker CB. HLA-Cw۶ and the ...
  • . Borroni RG, Costanzo A. HLA‐C* ۰۶ and psoriasis: susceptibility, ...
  • . Szczerkowska-Dobosz A, Rebala K, Szczerkowska Z, Witkowska-Tobola A. Correlation ...
    • نمایش کامل مراجع